Emerging evidence supports ketogenic diets as a metabolic adjunct for cancer; moderate strength for improving quality of life (QoL). Clinical trials indicate that ketogenic diets can significantly reduce fatigue in patients.

  • Overall Energy Boost: Improved perceived energy and physical function in women with ovarian or endometrial cancer after 12 weeks on ketogenic diet.
  • Inflammation Reduction: Significant improvement in C-reactive protein (CRP) levels with ketogenic diets lasting over 12 weeks; decreased TNF-α levels in breast cancer patients.
  • Quality of Life Enhancement: Improved emotional functioning and reduced insomnia in patients with advanced cancer.
  • Survival Benefits: Longer adherence to ketogenic diet (≥12 months) associated with median overall survival of 55.1 months vs. 12 months.
  • Anti-Tumor Synergy: Ketogenic diet combined with chemotherapy synergistically suppresses pancreatic tumor growth by disrupting metabolism.
  • Glucose Control: Ketogenic diets lead to decreased blood glucose levels in cancer patients, potentially sensitizing tumors to therapy.