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Appointment dossier — Glioblastoma

Bring this to your appointment. It summarizes what published studies report — it is not medical advice and does not say anything works. Decisions are yours and your care team’s.

Compounds studied in Glioblastoma

“Positive” means a study reported a positive result — most are early lab/animal work that may not translate to people.

Open recruiting trials (18)

Most-relevant first: trials that name Glioblastoma, then broader trials you may still qualify for. 322 recruiting trials name this cancer on ClinicalTrials.gov. Eligibility is decided by each trial's team — bring these NCT numbers to your appointment.

Financial help to look into

For each medicine above, search manufacturer and nonprofit programs at medicineassistancetool.org.

Questions to ask your oncologist

  1. I've read that Temozolomide has been studied in people for Glioblastoma — what's the evidence, and is it an option or available in a trial for me?
  2. I've read that Pembrolizumab has been studied in people for Glioblastoma — what's the evidence, and is it an option or available in a trial for me?
  3. Of the open trials I found (for example NCT06496971), am I eligible for any — here or at a larger cancer center?
  4. What is my exact diagnosis — the type, subtype, stage, and grade?
  5. Has my tumor had molecular or genomic testing (e.g. next-generation sequencing), and what did it find?
  6. Should I have inherited (germline) genetic testing, and could it affect my treatment or my family?
  7. What is the goal of treatment for me — cure, long-term control, or comfort?
  8. What are all of my standard treatment options, and what does each one involve?
  9. What is the realistic benefit of each option, in actual numbers?
  10. What are the most common and the most serious side effects, and how are they managed?
  11. How will we know if treatment is working, and how often will I be scanned or tested?
  12. If the first treatment doesn't work, what are the next options?
  13. Are there gentler options if I want to prioritize quality of life?
  14. Am I eligible for any clinical trials — here or at a larger/academic cancer center?
  15. Is my case reviewed by a multidisciplinary tumor board?
  16. Would a second opinion at a center that treats my cancer often be worthwhile?
  17. Could any of my prescriptions, over-the-counter drugs, or supplements interfere with treatment?
  18. Which symptoms are emergencies, and who do I call after hours?
  19. Should I see palliative or supportive care alongside my treatment?
  20. How will treatment affect my daily life, work, and (if it matters to me) fertility?
  21. What can I safely do myself — diet and activity — and is anything I'm taking risky?
  22. What will treatment cost, and is financial assistance available?