Glioblastoma: treatment map

Standard care plus compounds studied in the literature, organized by clinical readiness.

Educational only. This is not medical advice and not a recommendation. Confirm anything here with your oncology team.

Treatment map: Glioblastoma

Standard care plus every compound studied in the literature (each cited) and graded by evidence, organized by clinical readiness. A category, not a verdict that anything works — confirm anything here with your oncology team.

Interventions

Standard of care

Tested in people

Lab / animal

Named in lit.

Classes

Standard of care (0) Guideline option (7) Tested in people (36) Lab / animal only (1) Named in the literature (1)

Tested in people, by trial phase: Phase II ×1 · phase not reported ×35

Clinical evidence

Preclinical evidence

Standard of care

Guideline option

Tested in people

Lab / animal only

Named in the literature

Surgery & procedures

—

Radiotherapy

—

Chemotherapy

—

Targeted therapy

—

Immunotherapy

—

Supplements & natural agents

—

Other

—

Columns group into clinical evidence (used in, or tested on, people) and preclinical evidence (lab/animal, or only named in the literature). Cell = number of interventions; a dashed cell means none recorded there.

Established care — detail (7)

Chemotherapy

temozolomideAdjuvant (after surgery) · IDH-wildtype FDA-approved for this cancer.	—	Guideline option
temozolomideAdjuvant (after surgery) FDA-approved for this cancer.	—	Guideline option
temozolomideMaintenance FDA-approved for this cancer.	—	Guideline option
temozolomideFirst-line (advanced disease) FDA-approved for this cancer.	—	Guideline option
temozolomideAdjuvant (after surgery) · methylation at the O6-methylguanine-DNA methyltransferase (MGMT) promoter in cancer DNA FDA-approved for this cancer.	—	Guideline option
temozolomide FDA-approved for this cancer.	—	Guideline option

Targeted therapy

bevacizumab FDA-approved for this cancer.	—	Guideline option

Investigational & adjunct compounds — detail (38)

Phase II trial (1)

Meta-analysis (35)

Named in the literature

Lab / animal only

"Tested in people" rows show the highest trial phase found in that compound's cited human studies (Phase I–IV; "phase not reported" = a human study with no phase tag). "Studied" = named in the cited literature for this cancer. "FDA ✓" = FDA-approved for this cancer; "off-label" = an FDA-approved drug used outside its approved indications (per openFDA). Not a claim that anything works.