Appointment dossier — Squamous Cervical Carcinoma
Bring this to your appointment. It summarizes what published studies report — it is not medical advice and does not say anything works. Decisions are yours and your care team’s.
Compounds studied in Squamous Cervical Carcinoma
- Cisplatin — Human evidence · 1 positive · PMID 23151423
- Topotecan — Human evidence · 1 positive · PMID 23151423
- Trastuzumab Deruxtecan — Human evidence · 1 positive · PMID 39639215
- Trastuzumab-Deruxtecan (T-Dxd) — Human evidence · 1 positive · PMID 39639215
- Pembrolizumab — Animal evidence · 1 positive · PMID 37469254
“Positive” means a study reported a positive result — most are early lab/animal work that may not translate to people.
Open recruiting trials (18)
- NCT06515990 · Phase 1 / Phase 2 — A Study of DM005 in Patients With Advanced Solid Tumors (United States)
- NCT07341737 · Phase 1 / Phase 2 — SL-28 for Advanced Solid Tumours (Australia)
- NCT06710756 · Phase 1 / Phase 2 — Lead-212 PSV359 Therapy for Patients With Solid Tumors (United States)
- NCT05751512 · Phase 3 — A Study to Evaluate MRG003 vs Cetuximab/Methotrexate in in the Treatment of Patients With RM-SCCHN (China)
- NCT06064877 · Phase 3 — A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma (United States)
- NCT05495152 · Phase 3 — Adjuvant Sintilimab for Locally Advanced Esophageal Squamous Cell Carcinoma (China)
- NCT04328948 · Phase 3 — A Randomized Controlled Trial Evaluating of Prophylactic Irradiation in CRT for cT1bN0M0 ESCC (Japan)
- NCT06030440 · Phase 2 / Phase 3 — De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck (Germany)
- NCT06052839 · Phase 2 — Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC (United States)
- NCT06452602 · Phase 2 — Induction Immunochemotherapy Followed by Concurrent Chemoradiotherapy in Patients With ESCC. (China)
- NCT06306846 · Phase 2 — Neoadjuvant SBRT in Localized Advanced HNSCC (China)
- NCT06494995 · Phase 2 — AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy (China)
- NCT06339619 · Phase 2 — Combination Immunotherapy of Adebrelimab With Apatinib and Tegafur, Gimeracil and Oteracil Potassium Capsules for Immune Rechallenge Therapy in Esophageal Squamous Cell Carcinoma (China)
- NCT06636734 · Phase 2 — Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial (United States)
- NCT06137274 · Phase 2 — Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC (United States)
- NCT06940180 · Phase 2 — Toripalimab With Chemotherapy for Sinus Cancer (United States)
- NCT06356688 · Phase 2 — A Clinical Study on the Efficacy and Safety of Paclitaxel Polymeric Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma (China)
- NCT06769698 · Phase 2 — A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (United States)
Most-relevant first: trials that name Squamous Cervical Carcinoma, then broader trials you may still qualify for. 653 recruiting trials name this cancer on ClinicalTrials.gov. Eligibility is decided by each trial's team — bring these NCT numbers to your appointment.
Financial help to look into
- PAN Foundation — Copay assistance funds by diagnosis (funds open and close as money allows). https://www.panfoundation.org/
- HealthWell Foundation — Copay and premium assistance funds by disease. https://www.healthwellfoundation.org/
- CancerCare — financial assistance — Limited grants plus free financial counseling. https://www.cancercare.org/financial
- Family Reach — Help with everyday living costs (rent, transport, food) during treatment. https://familyreach.org/
- NeedyMeds — Searchable directory of drug patient-assistance and discount programs. https://www.needymeds.org/
For each medicine above, search manufacturer and nonprofit programs at medicineassistancetool.org.
Questions to ask your oncologist
- I've read that Cisplatin has been studied in people for Squamous Cervical Carcinoma — what's the evidence, and is it an option or available in a trial for me?
- I've read that Topotecan has been studied in people for Squamous Cervical Carcinoma — what's the evidence, and is it an option or available in a trial for me?
- I've read that Trastuzumab Deruxtecan has been studied in people for Squamous Cervical Carcinoma — what's the evidence, and is it an option or available in a trial for me?
- Of the open trials I found (for example NCT06515990), am I eligible for any — here or at a larger cancer center?
- What is my exact diagnosis — the type, subtype, stage, and grade?
- Has my tumor had molecular or genomic testing (e.g. next-generation sequencing), and what did it find?
- Should I have inherited (germline) genetic testing, and could it affect my treatment or my family?
- What is the goal of treatment for me — cure, long-term control, or comfort?
- What are all of my standard treatment options, and what does each one involve?
- What is the realistic benefit of each option, in actual numbers?
- What are the most common and the most serious side effects, and how are they managed?
- How will we know if treatment is working, and how often will I be scanned or tested?
- If the first treatment doesn't work, what are the next options?
- Are there gentler options if I want to prioritize quality of life?
- Am I eligible for any clinical trials — here or at a larger/academic cancer center?
- Is my case reviewed by a multidisciplinary tumor board?
- Would a second opinion at a center that treats my cancer often be worthwhile?
- Could any of my prescriptions, over-the-counter drugs, or supplements interfere with treatment?
- Which symptoms are emergencies, and who do I call after hours?
- Should I see palliative or supportive care alongside my treatment?
- How will treatment affect my daily life, work, and (if it matters to me) fertility?
- What can I safely do myself — diet and activity — and is anything I'm taking risky?