Case reportTrialReported positiveLimited evidenceTier 3 · early humann = 2
Primary ovarian rhabdomyosarcoma in children
Pediatric surgery international · May 2008 · case reports
CyclophosphamideVincristineDoxorubicinovarian rhabdomyosarcomaalveolar rhabdomyosarcomaembryonal rhabdomyosarcoma
This report describes two children with very rare primary ovarian rhabdomyosarcoma. After complete surgical removal, both received chemotherapy with vincristine, doxorubicin, and cyclophosphamide and had a good response. Both patients were alive 8 and 9 months after surgery.
Key findings
- Two pediatric cases of primary ovarian rhabdomyosarcoma were described.
- Both patients underwent complete resection of the primary tumor.
- Both received vincristine, doxorubicin, and cyclophosphamide chemotherapy.
- The abstract reports a good response to therapy and survival at 8 and 9 months post-operatively.
Limitations: Case report with only 2 patients.; No control group.; Short follow-up.; Cannot separate the effect of surgery from chemotherapy.; No dosing details reported..
Describes management of a rare ovarian cancer in children, including chemotherapy, but does not isolate the effect of any single compound.
AI summary of the abstract, human-reviewed · Jun 2026. Describes what this study reported, not medical advice. View on PubMed